SARM (selective androgen receptor modulator) is a special type of molecule that scientists have developed to cure diseases previously treated unsuccessfully with anabolic androgenic steroids. There are a number of SARMs that have undergone trial for TRT.
SARM is able to demonstrate anabolic and hypertrophic activity when it comes in contact with the receptor and binds it. This is the reason why it is suitable for use in osteoporosis and muscle wasting treatment. Some SARM possesses an anabolic to androgenic ratio of up to 10:1 which allows them to develop muscle mass without the user experiencing any side effect.
SARM was first invented in the 1940s by making modifications to the testosterone molecule. The first SARM that was invented is steroidal but many large firms are carrying out R&D to produce non steroidal SARM today. Through research, they are decreasing the hepatic toxicity that these compounds create.
There is a difference between steroidal and non steroidal SARM. Steroidal SARM can induce the protein synthesis process in all cells. On the other hand, non steroidal SARM will only affect the parts of the DNA that has to do with preventing muscle and bone wasting. SARM (selective androgen receptor modulator) is able to improve the muscle mass without increasing the estrogen or causing problem to pituitary gland.
They have done research on the benefit to harm ratio of non steroidal and found out that the benefit far out weight the side effects it carries. Non steroidal SARM is safer but it also requires a longer period of use to achieve the same result when compared to a steroid SARM.
There are various types of SARMs including LGD-4033, Ostarine MK-2866, MK677, and RAD140. LGD-4033 is a type of non steroidal supplement that can improve lean muscle mass and lower the amount of excess fat in the body. It is 12 times more potent than Ostarine and you only have to take 1/3 of the dose. It is suppressive to the HPTA system so doctors would often recommend a SERM post cycle.
Ostarine MK-288 is good for maintenance of lean body mass. SERM PCT is required in a longer high dose cycle of OStarine. Some people claim that they experience gyno after taking it. Therefore, it is advised that you have Al handy with you.
MK677 (Ibutamoren) is useful in enhancing the muscle and bone mass. It imitates the ghrelin hormone and can regulate your appetite. It does not require any PCT following the cycle. It is best taken in a 3 months cycle and you can slowly increase the dosage every month. The best time to take MK677 is at night just before your sleeping time. It is common for the users to experience numbness in the hands when they wake up.
RAD140 is the latest SARM used primarily in building muscles and curing Alzheimer. It has an impressive anabolic to androgenic ratio of 90:1. It offers muscle building effects without causing the side effects from taking androgen. RAD140 can effectively limit the testosterone effect on the unwanted areas.
Oral SARM can reduce the risk of the spike of the testosterone level the in the blood which can lead to prostate problem. It also reduce the chances of developing diseases that steroids can cause. Now there is about 1/10 of the population using non steroidal SARM as it becomes increasingly popular.
Because SARM is non toxic, it will not cause damage on your liver. You also don’t have to take preloading and oncycle support supplements. It will not cause bone loss that can happen as a result of taking testosterone. It does not involve any estrogen conversion. Finally, taking part in a SARM cycle will be cheaper than taking part in a steroid or prohormone cycle. There is also a lower chance of causing estrogen and water retention side effects.